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NFL Week 12 Odds – Opening Betting Lines & Spreads for All Games
by Robert Duff in NFL Football
Updated Nov 19, 2023 · 5:41 PM PST
Nov 19, 2023; Houston, Texas, USA; Arizona Cardinals quarterback Kyler Murray (1) huddles against the Houston Texans in the second half at NRG Stadium. Mandatory Credit: Thomas Shea-USA TODAY SportsNFL Week 12 kicks off with three Thursday games on ThanksgivngFor the first time ever, there’s a Black Friday contest between the Dolphins and JetsA look at all the opening NFL Week 12 odds can be found below with early predictions
The NFL Week 12 slate of games is offering some traditional rivalry fare on Thanksgiving to kick off the week, with the Green Bay Packers in Detroit to face the Lions and the Dallas Cowboys playing host to the Washington Commanders.
Baltimore is back in prime time for a second straight week. Fresh off their TNF divisional win over the Bengals, the Ravens are in Los Angeles to face the Chargers on Sunday Night Football.
There’s also a Super Bowl 42 and 46 rematch on tap as the New England Patriots visit the New York Giants. It’s unlikely, though, that many will be clamoring to check out this tilt between the 2-8 Patriots and the 3-8 Giants.
Opening NFL Week 12 Odds
| Team | Moneyline | Spread | Over/Under |
|---|---|---|---|
| Green Bay Packers | +290 | +7.5 (-115) | Over 45.5 (-110) |
| Detroit Lions | -360 | -7.5 (-105) | Under 45.5 (-110) |
| Team | Moneyline | Spread | Over/Under |
| San Francisco 49ers | -280 | -6.5 (-110) | Over 43.5 (-115) |
| Seattle Seahawks | +230 | +6.5 (-110) | Under 43.5 (-105) |
| Team | Moneyline | Spread | Over/Under |
| Washington Commanders | +425 | +11 (-110) | Over 46.5 (-115) |
| Dallas Cowboys | -550 | -11 (-110) | Under 46.5 (-105) |
| Team | Moneyline | Spread | Over/Under |
| Miami Dolphins | -360 | -7 (-120) | Over 42.5 (-105) |
| New York Jets | +290 | +7 (EVEN) | Under 42.5 (-115) |
| Team | Moneyline | Spread | Over/Under |
| Tampa Bay Buccaneers | +105 | +1.5 (-110) | Over 42.5 (-110) |
| Indianapolis Colts | -125 | -1.5 (-110) | Under 42.5 (-110) |
| Team | Moneyline | Spread | Over/Under |
| New England Patriots | -185 | -3.5 (-110) | Over 33.5 (-110) |
| New York Giants | +155 | +3.5 (-110) | Under 33.5 (-110) |
| Team | Moneyline | Spread | Over/Under |
| Pittsburgh Steelers | EVEN | +1 (-110) | Over 35.5 (-110) |
| Cincinnati Bengals | -120 | -1 (-110) | Under 35.5 (-110) |
| Team | Moneyline | Spread | Over/Under |
| Carolina Panthers | +165 | +4 (-110) | Over 37.5 (-105) |
| Tennessee Titans | -195 | -4 (-110) | Under 37.5 (-115) |
| Team | Moneyline | Spread | Over/Under |
| Jacksonville Jaguars | -110 | -1 (-110) | Over 45.5 (-115) |
| Houston Texans | -110 | +1 (-110) | Under 45.5 (-105) |
| Team | Moneyline | Spread | Over/Under |
| New Orleans Saints | -110 | +1 (-120) | Over 41.5 (-105) |
| Atlanta Falcons | -110 | -1 (EVEN) | Under 41.5 (-115) |
| Team | Moneyline | Spread | Over/Under |
| Los Angeles Rams | -115 | -1 (-120) | Over 46 (-115) |
| Arizona Cardinals | -105 | +1 (-102) | Under 46 (-105) |
| Team | Moneyline | Spread | Over/Under |
| Cleveland Browns | -102 | +1.5 (-110) | Over 36.5 (-110) |
| Denver Broncos | -122 | -1.5 (-110) | Under 36.5 (-110) |
| Team | Moneyline | Spread | Over/Under |
| Buffalo Bills | +142 | +3.5 (-115) | O 47.5 (-110) |
| Philadelphia Eagles | -170 | -3.5 (-105) | U 47.5 (-110) |
| Team | Moneyline | Spread | Over/Under |
| Kansas City Chiefs | -455 | -10 (-110) | Over 44 (-110) |
| Las Vegas Raiders | +350 | +10 (-110) | Under 44 (-110) |
| Team | Moneyline | Spread | Over/Under |
| Baltimore Ravens | -185 | -4 (-110) | Over 46 (-110) |
| Los Angeles Chargers | +154 | +4 (-110) | Under 46 (-110) |
| Team | Moneyline | Spread | Over/Under |
| Chicago Bears | +150 | +3.5 (-110) | Over 45.5 (-110) |
| Minnesota Vikings | -180 | -3.5 (-110) | Under 45.5 (-110) |
The NFL odds for Week 12 are showing the Dallas Cowboys as the biggest favorites. They’re the 10-point chalk in their game at home to the Commanders.
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Four games are opening with the lowest odds, all with betting lines of one points. They include the Los Angeles Rams as the 1.5-point away chalk over the Arizona Cardinals. Arizona was briefly the 1-point favorite in this game. It was the first time in 20 games that the Cardinals are set as the favorites in the betting line.
The Week 12 total high of 47.5 points arrives with the contest between the Buffalo Bills and the reigning NFC Champion Philadelphia Eagles. The smallest in the 33.5 points assigned to the New England Patriots vs New York Giants game.
The reigning-champion Chiefs continue to lead the Super Bowl odds at +450. Philadelphia (5-2-2) owns the best ATS cover rate in the NFL at 71.4%.
Ravens vs Chargers Early Odds & Predictions
The Chargers are 0-3 against the spread as an underdog this season, so opening as 4-point home underdogs doesn’t bode well for Justin Herbert and company.
Baltimore, though, is just 2-3 ATS in the last five against the Chargers. Then again, the Ravens are 1-0 ATS against them in LA. Baltimore is 3-2 ATS on the road this season.
Pick: Ravens -4 (-110)
Super Bowl 59 Odds for 2025: 49ers Open as Favorites, But Chiefs Are Close SecondRead More
Opening Bears vs Vikings Odds & Predictions
With QB1 Justin Fields back from his dislocated thumb last week, Chicago put a scare into the NFC North-leading Detroit Lions before succumbing 31-26. Could the Bears do it again facing Minnesota, the #2 team in the division?
Justin Fields asked about his finger injury…… whoops pic.twitter.com/gilBB267Qm
— Ari Meirov (@MySportsUpdate) November 20, 2023
Chicago 4-1 ATS in the last five games at Minnesota. The Bears are 2-0 SU and 1-1 ATS in prime time this season. They’re 0-3 SU and 1-2 ATS within the division.
Pick: Vkings -3.5 (-110)
Expected Week 12 Line Movement
Oddsmakers briefly favoring the Cardinals for the first time since they were a 2-point home pick over Seattle on Oct. 16, 2022, oddly enough saw the Seahawks are playing a role again in Arizona being favored.
Riq Woolen sniffs out the trick play and gets an INT!
📺: #SEAvsLAR on CBS📱: Stream on #NFLPlus https://t.co/jckqnJwdb2 pic.twitter.com/FLDgC7zPdJ
— NFL (@NFL) November 19, 2023
Rams QB1 Matthew Stafford was injured in Sunday’s game against Seattle. He was able to finish out LA’s victory, though, so that’s likely why the line swing back to LA. This will be a developing story to track during the week.
Pick: Rams -1 (-110)
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